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Dr. Shahneaz Ali Khan
Professor and Head
Department of Physiology Biochemistry and Pharmacology
Faculty of Veterinary Medicine


About
Qualifications
Publications
Funding



Dr. Shahneaz Ali Khan has a distinguished academic and professional background in veterinary medicine, biochemistry, and molecular biology. After earning his Doctor of Veterinary Medicine (DVM) degree from Chittagong University, he pursued an MPhil in Biochemistry and Molecular Biology. His career took a pivotal turn when he joined Eco Health Alliance in New York as a research scientist, where he studied the impact of the Nipah virus in fruit bats and its implications for livestock health. This experience laid the foundation for his ongoing research in public health and veterinary sciences.

Upon returning to Bangladesh, Dr. Khan joined Chittagong Veterinary and Animal Sciences University (CVASU) in 2008, initially as a lecturer in the Department of Physiology, Biochemistry, and Pharmacology. He later advanced to the position of Assistant Professor. His work at CVASU has been marked by fruitful collaborations with international organizations such as the Food and Agriculture Organization (FAO), the International Centre for Diarrhoeal Disease Research (ICDDR,B), and Eco Health Alliance.

Dr. Khan's academic journey continued with a PhD from Queensland University of Technology, under the guidance of Professor Peter Timms, focusing on the development of a chlamydial vaccine for koalas. His research has contributed significantly to the field, with numerous publications in prestigious journals such as Vaccine, PLOS One, mBio, PLOS Pathogens, Emerging Infectious Diseases (EID), and Preventive Veterinary Medicine.

His research interests cover a broad range of critical issues in public health and veterinary medicine, with a particular focus on:

1. Vector-Borne Diseases (VBDs) and One Health Approach

  • Monitoring and assessing the risks of vector-borne diseases in Bangladesh, especially in collaboration with European universities.
  • Promoting the One Health approach, which connects human, animal, and environmental health.

2. Antimicrobial Resistance (AMR) and Public Health

  • Investigating antimicrobial resistance across ecosystems, focusing on its transfer from animals to humans via the food chain, particularly through poultry and fish.
  • Addressing antimicrobial use in veterinary practices and its impact on the emergence of multi-drug-resistant bacteria.

3. Molecular Epidemiology and Zoonotic Diseases

  • Studying zoonotic diseases like multi-drug-resistant Escherichia coli and viruses like Nipah and Hepatitis E.
  • Investigating the transmission dynamics of these diseases, especially their spillover from wildlife to humans.

4. Food Safety and Veterinary Medicine

  • Exploring food safety issues, particularly antimicrobial residues in animal-origin foods and their public health implications.

5. Environmental Health and Pesticide Exposure

  • Examining the toxic effects of pesticide exposure from agricultural practices on human health through environmental contamination.
  • Using animal models to study these impacts, particularly in Bangladesh.

6. Wildlife and Environmental Health

  • Focusing on infectious diseases in wildlife populations and the role of wildlife in emerging zoonotic diseases, including research on Chlamydia in koalas.

7. Epidemiological Surveys and Public Health Behavior

  • Assessing public health knowledge, attitudes, and practices in Bangladesh, particularly regarding diseases like tuberculosis and COVID-19.

8. Emerging Infectious Diseases and Pandemic Preparedness

  • Researching emerging infectious diseases, particularly bat-borne viruses like Nipah, and strategies for improving pandemic preparedness in resource-limited settings.

Dr. Khan has also been awarded various grants, such as the WWCT Award from the Whitley Wildlife Conservation Trust, the Columbus Zoo Conservation Fund, and the University Grant Commission Research Award. His extensive contributions to research and public health make him a key figure in advancing knowledge on zoonotic diseases, antimicrobial resistance, and the One Health approach to safeguard the health of humans, animals, and the environment.






Research Interests


Contact

Email:
shahneaz@cvasu.ac.bd
shahneazbat@gmail.com

Cell Phone:   +8801999527495

T&T:    +88 031 659093 (Ex 373)

Fax:   + 88 031 659620

Location

302, Old Academic Building ; 2nd Floor, Faculty of Veterinary Medicine,
Chattogram City.

Qualifications


Educational Qualifications

PhD 

Queensland University of Technology

Brisbane , Australia 

Mphil 

Chittagong University 

Chattogram, Bangladesh 

DVM

Chittagong University 

Chattogram , Bangladesh 


Honours


Publications


  • Mim, Z.T.; Nath, C.; Sattar, A.A.; Rashid, R.; Abir, M.H.; Khan, S.A.; Kalam, M.A.; Shano, S.; Cobbold, R.; Alawneh, J.I.; et al. (2024). Epidemiology and Molecular Characterisation of Multidrug-Resistant Escherichia coli Isolated from Cow Milk. Vet. Sci., 11, 609. https://doi.org/10.3390/vetsci11120609

  • Tanzin, A.Z.; Nath, C.; Nayem, M.R.K.; Sayeed, M.A.; Khan, S.A.; Magalhaes, R.S.; Alawneh, J.I.; Hassan, M.M. (2024). Detection and Characterisation of Colistin-Resistant Escherichia coli in Broiler Meats. Microorganisms, 12, 2535. https://doi.org/10.3390/microorganisms12122535

  • Ábrahám Á, Islam MN, Gazdag Z, Khan SA, Chowdhury S, Kemenesi G, Akter S. (2024). Bacterial Metabarcoding of Raw Palm Sap Samples from Bangladesh with Nanopore Sequencing. Foods, 13(9):1285. https://doi.org/10.3390/foods13091285

  • Lanszki Z, Islam MS, Shikder MF, Sarder MJU, Khan SA, Chowdhury S, Islam MN, Tauber Z, Tóth GE, Jakab F, Kemenesi G, Akter S. (2024). Snapshot study of canine distemper virus in Bangladesh with on-site PCR detection and nanopore sequencing. Sci Rep., 14(1):9250. https://doi.org/10.1038/s41598-024-59343-6

  • Alam GS, Hassan MM, Ahaduzzaman M, Nath C, Dutta P, Khanom H, Khan SA, Pasha MR, Islam A, Magalhaes RS, Cobbold R. (2023). Molecular Detection of Tetracycline-Resistant Genes in Multi-Drug-Resistant Escherichia coli Isolated from Broiler Meat in Bangladesh. Antibiotics (Basel), 12(2):418. https://doi.org/10.3390/antibiotics12020418

  • Khan SA, Imtiaz MA, Islam MM, Tanzin AZ, Islam A, Hassan MM. (2022). Major bat-borne zoonotic viral epidemics in Asia and Africa: A systematic review and meta-analysis. Veterinary Medicine and Science, 8(4):1787-1801. https://doi.org/10.1002/vms3.835

  • Shaikat, A.H., Khan, S.A., Imtiaz, M.A. et al. (2022). Assessing the health hazard originated via pesticide chemicals in humans through rabbit model in agricultural production system in Bangladesh. BMC Pharmacology and Toxicology, 23:28. https://doi.org/10.1186/s40360-022-00567-5

  • Kalam MA, Rahman MS, Alim MA, Shano S, Afrose S, Jalal FA, Akter S, Khan SA, Islam MM, Uddin MB, Islam A, Magalhães RJS, Hassan MM. (2022). Knowledge, Attitudes, and Common Practices of Livestock and Poultry Veterinary Practitioners Regarding the AMU and AMR in Bangladesh. Antibiotics (Basel), 11(1):80. https://doi.org/10.3390/antibiotics11010080

  • Owada K, Sarkar J, Rahman MK, Khan SA, Islam A, Hassan MM, Soares Magalhães RJ. (2022). Epidemiological Profile of a Human Hepatitis E Virus Outbreak in 2018, Chattogram, Bangladesh. Tropical Medicine for Infectious Diseases, 7(8):170. https://doi.org/10.3390/tropicalmed7080170

  • Kalam MA, Alim MA, Shano S, Nayem MRK, Badsha MR, Mamun MAA, Hoque A, Tanzin AZ, Khan SA, Islam A, Islam MM, Hassan MM. (2021). Knowledge, Attitude, and Practices on Antimicrobial Use and Antimicrobial Resistance among Poultry Drug and Feed Sellers in Bangladesh. Veterinary Science, 8(6):111. https://doi.org/10.3390/vetsci8060111

  • Hassan MM, Kalam MA, Alim MA, Shano S, Nayem MRK, Badsha MR, Al Mamun MA, Hoque A, Tanzin AZ, Nath C, Khanom H, Khan SA, Islam MM, Uddin MB, Islam A. (2021). Knowledge, Attitude, and Practices on Antimicrobial Use and Antimicrobial Resistance among Commercial Poultry Farmers in Bangladesh. Antibiotics (Basel), 10(7):784. https://doi.org/10.3390/antibiotics10070784

  • Khan SA, Sayed MA, Shaikat AH, Shawn MAI, Hassan MM. (2020). Antimicrobial resistance pattern in domestic animal-wildlife-environment niche via the food chain to human in Bangladesh perspective: A review. BMC Veterinary Research, 16:302.

  • Hassan MM, El Zowalaty ME, Lundkvist Å, Järhult JD, Khan MRN, Tanzin AZ, Badsha MR, Khan SA, Ashour HM. (2021). Residual antimicrobial agents in food originating from animals. Trends in Food Science & Technology. https://doi.org/10.1016/j.tifs.2021.01.075

  • Epstein JH, Anthony SJ, Islam A, Marm Kilpatrick A, Khan SA, Balkey MD, Ross N, Smith I, Zambrana-Torrelio C, Tao Y, Islam A, Quan PL, Olival KJ, Khan MSU, Gurley ES, Hossein MJ, Field HE, Fielder MD, Briese T, Rahman M, Broder CC, Crameri G, Wang LF, Luby SP, Lipkin W, Daszak P. (2020). Nipah virus dynamics in bats and implications for spillover to humans. Proceedings of the National Academy of Sciences, 117(46):29190-29201. https://doi.org/10.1073/pnas.2000429117

  • Hassan MM, Kalam M, Alam M, Shano S, Faruq AA, Hossain M, Islam M, Khan SA, Islam A. (2020). Understanding the Community Perceptions and Knowledge of Bats and Transmission of Nipah Virus in Bangladesh. Animals, 10(10):1814.

  • Hassan MM, Kalam MA, Shano S, Nayem MRK, Rahman MK, Khan SA, Islam A. (2020). Assessment of Epidemiological Determinants of COVID-19 Pandemic Related to Social and Economic Factors Globally. Journal of Risk and Financial Management, 13(9):1-14.

  • Hassan MM, El Zowalaty ME, Islam A, Khan SA, Rahman MK, Järhult JD, Hoque MA. (2020). Prevalence and Diversity of Avian Influenza Virus Hemagglutinin Sero-Subtypes in Poultry and Wild Birds in Bangladesh. Veterinary Sciences, 7(2):73.

  • Miazi OF, Khan MK, Miah G, Hassan MM, Khan SA. (2020). Fertility, hatchability and livability up to first laying age of Aseel and F1 of Hilly (Red Jungle × Hilly) chicken under intensive rearing system. Bangladesh Journal of Veterinary and Animal Sciences, 8(1).

  • Akter H, Shaikat A, Imtiaz MA, Islam A, Khan SA, Hassan MM. (2019). Prevalence and multidrug resistance pattern of Escherichia coli isolated from street food. Bangladesh Journal of Veterinary and Animal Sciences, 7(2).

  • Nyari S, Khan SA, Rawlinson G, Waugh CA, Potter A, Gerdts V, Timms P. (2018). Vaccination of koalas (Phascolarctos cinereus) against Chlamydia pecorum using synthetic peptides derived from the major outer membrane protein. PLOS One, 13(6):e0200112. https://doi.org/10.1371/journal.pone.0200112

  • Desclozeaux M, Robbins A, Jelocnik M, Khan SA et al. (2017). Immunization of a wild koala population with a recombinant Chlamydia pecorum Major Outer Membrane Protein (MOMP) or Polymorphic Membrane Protein (PMP) based vaccine: New insights into immune response, protection and clearance. PLOS One.


Funding


Current Funding

1. Antimicrobial Residue in the Human Food ChainCompleted

  • This project focused on identifying and addressing the presence of antimicrobial residues in food that could potentially enter the human food chain, impacting public health and contributing to AMR.

2. Bangladesh Bureau of Educational Information & Statistics (BANBEIS)Completed

  • Project number SD 2019967, which likely involved compiling and analyzing educational data in Bangladesh to support health and public awareness campaigns, potentially linked to AMR or zoonotic diseases.

3. Antimicrobial Resistant Pattern and Genotyping of Multidrug-Resistant E. coli from Fruits, Birds, and FishCVASU & UGC

  • This project, conducted by the University of Paces and Chattogram Veterinary and Animal Sciences University (CVASU), aimed to identify antimicrobial resistance patterns in E. coli found in fruits, Sonali chicken, quail, and fish, which are critical in understanding the spread of AMR through food sources.

4. Diversity of Bat Species Across BangladeshUGC & CVASU

  • This study focused on mapping the diversity of bat species across Bangladesh. Bats are often reservoirs for zoonotic diseases like rabies and Ebola, so understanding their distribution is key for monitoring potential public health risks.

5. VECTORACT Project: Building Knowledge Capacity for Vector-Borne Diseases

  • Project Name: VECTORACT
  • Acronym: VECTORACT
  • Coordinator Contact: Gábor KEMENESI, Eötvös Loránd University (ELTE), Hungary
  • Objective: To build both practical and theoretical knowledge to monitor, assess, and mitigate the risks of vector-borne diseases, such as malaria, dengue, and chikungunya, in Bangladesh.
  • Consortium Members:
    • Eötvös Loránd University (ELTE), Hungary (Coordinator)
    • Veterinärmedizinische Universität Wien (UVMV), Austria
    • Chattogram Veterinary and Animal Sciences University (CVASU), Bangladesh
    • University of Rajshahi (RU), Bangladesh

6. Bangladesh Systems Strengthening for One Health Activity

  • Objective: This comprehensive initiative, a collaboration between DAI, USAID, CVASU, and the One Health Institute, aims to build Bangladesh's capacity to prevent, detect, and respond to zoonotic diseases, emerging infectious diseases, and AMR. The focus is on enhancing disease surveillance, improving diagnostics, and addressing the misuse of antibiotics and other antimicrobial agents.
  • Key Elements:
    • One Health Approach: The project applies a One Health approach, which recognizes the interconnectedness of human, animal, and environmental health. This integrated approach is crucial for managing the risks posed by zoonotic diseases and AMR.
    • Strengthening Local Institutions: The initiative aims to enhance local institutions, like CVASU, to ensure the sustainability of health interventions and a long-term impact.

Expected Outcomes of the One Health Initiative:

  • Improved Disease Surveillance and Early Warning Systems: Enhanced detection systems for quicker responses to emerging diseases.
  • Stronger Health Systems: Both human and animal health systems are strengthened to handle infectious disease outbreaks effectively.
  • Reduction in AMR: The project targets reducing AMR through better antimicrobial use practices in both human and animal health.
  • Sustainability: Long-term sustainability through capacity-building within local institutions, particularly universities and health organizations, to continue monitoring and combating zoonotic diseases and AMR.

Conclusion:

These projects collectively contribute to improving Bangladesh's health system, particularly its ability to detect and manage infectious diseases and antimicrobial resistance through a One Health approach. By integrating efforts across various sectors — including veterinary medicine, environmental health, and public health — these initiatives provide a comprehensive framework for addressing the risks posed by zoonotic diseases, AMR, and vector-borne diseases. They also focus on ensuring sustainability and local capacity to respond to future health challenges.




Supervision


Collaboration